TLC will launch its first late-night talk show in January dubbed All About Sex, the network said Friday.

The weekly, female-targeted series will feature actress Margaret Cho, media personalities Heather McDonald and Marissa Jaret Winokur, and sex expert Dr. Tiffanie Davis Henry exploring issues around sex and relationships, according to  the network.

The six-episode series will debut Jan. 10, following new episode premieres of the network’s Sex Sent Me To the ER series.

All About Sex will be produced by Relativity Television and Ellen Rakieten Entertainment for TLC.